Author Archives: puddleg58

A short guide to reverse cholesterol transport

Cholesterol is a molecule required by every cell of the body in fairly large amounts. It can be easily synthesised by these cells, or taken up by them from LDL and other ApoB lipoproteins, but cannot be broken down. Cholesterol is not soluble in water, and thus must be carried through the blood on lipoprotein […]

The Empire Strikes Back – American Heart Association gets Presidential on Saturated Fats.

These days most people associate the word “Presidential” with a lot of bluster that tends to disguise real problems and do more harm than good, as well as a partisan approach to any question. In the US at least, being “presidential” means a pathological inability to admit error, and a cavalier approach to the evidence […]

Defending LCHF in the climate change debate

Our last post which questioned in passing aspects of the plant-based position on climate change caused quite a fuss in some circles. We were accused of being science-deniers, on a par with Trump and the anti-vaxxers, by some. There’s a recent blog about us here. The atmosphere is warming, the sea levels are rising, species […]

Red Meat Will Kill You – and make it look like an accident.

By George Henderson and Grant Schofield Disclaimer – we’re not recommending that people eat red meat in preference to white meat, anymore than we think people should eat red peppers instead of onions. A mixed diet of various types of animal and plant foods, as close to nature as is consistent with good hygiene, good […]

NZ case study; A citizen scientist controls autoimmune diabetes without insulin, with a low carb diet, a glucose meter, and metformin.

The case study is a very important type of medical publication that’s overlooked in this age of big data. Unlike large statistical studies, which tell you the probability of something happening, the case study tells you whether something CAN happen at all, and under exactly which circumstances it has happened. Case studies answer questions like […]

The BROAD study – a super-low fat vegan intervention for weight loss

By George Henderson and Grant Schofield There are few diet trials published from New Zealand, so we’re always keen to see them; and there are even fewer vegan diet trials. We are even more interested when they go beyond their data, and start in on a sort of zealot approach to running down low carb diets […]

What Really Happens to Saturated Fat on a Low Carb Diet?

In our last post, we went into a lot of detail about specific types of saturated fat and their effects on HDL. Here, we’ll try to summarise that information, and highlight some interesting conclusions, in simpler language. But first, a short chemistry lesson. Nothing too hard, hopefully – we’ll just focus on the main dietary […]

Diet and HDL; the effect of myristic acid vs carbohydrate.

The nutrients that raise and lower HDL and ApoA1. So is getting your HDL high a good thing?  It probably depends if you earned it or not…..and what you eat especially myristic acid This very interesting study from 2014 brings into focus many of our recent posts about HDL, TG/HDL, ApoB/ApoA1 in the context of […]

Dietary Guidelines – our letter in The Lancet

If anyone’s interested in the public health nutrition debate around the dietary guidelines, then here’s a summary and critique of our latest jousting round(s) with conventional wisdom. In late 2016, an article from New Zealand in defense of the current dietary guidelines was published in the renowned medical journal The Lancet. While the authors (who included Prof […]

Margarines, Cooking Oils, and Non-dairy Spreads – is there enough evidence for benefit or harm?

How much evidence do you need to make recommendations about what the public should eat? It depends really. “On fair evidence we might take action on what appears to be an occupational hazard. For example, we might change from a probably carcinogenic oil to a non-carcinogenic oil in a limited environment and without too much […]

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